Nephrotic syndrome and thymoma recurrence: a case report
Article Sidebar
Main Article Content
Abstract
Paraneoplastic syndromes, such as myasthenia gravis, pure red-cell aplasia and systemic lupus erythematosus are well-documented in thymoma. Association with glomerulopathies is rare and may occur several years after thymectomy. We report a case of a 60-year-old male presenting with nephrotic syndrome after thymectomy due to thymoma. The kidney biopsy showed minimal change disease. The patient went into complete remission after treatment with corticosteroids. The pathogenesis of glomerular lesions associated with thymic disease remains controversial.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
Monga D, Jhaveri KD. Chapter 6: Glomerular Diseases and Cancer. Am Soc Nephrol. 2016;1–9. https://www.asn-online.org/education/distancelearning/curricula/onco/Chapter6.pdf.
Karras A, de Montpreville V, Fakhouri F, Grünfeld JP, Lesavre P, Dracon M, et al. Renal and thymic pathology in thymona-associated nephropathy: Report of 21 cases and review of the literature. Nephrol Dial Transplant. 2005;20 (March):1075–82.
Hsiao S-Y, Chang K-Y, Chang J-Y, Su W-C. Nephrotic Syndrome Associated with Thymoma. Táiwān Áizhèng Yīxué Zázhì [Internet]. The Chinese Oncology Society; 2014;1(3):233–40.
Mayrs EBC. The nephrotic syndrome. Br Med J. 1954;1(4856):273.
Nakamura T, Matsuyamat M, Kojimat A, Ogiut T, Kubota A, Suzuki Y. i The effect of thymectomy on the development of nephropathy in spontaneous thymoma rats of the BUF/Mna strain. 1988;350–2.